Search results for "Antifungal therapy"

showing 5 items of 5 documents

Candida thrombophlebitis in children: a systematic review of the literature

2020

Abstract Objective To describe a case of thrombophlebitis associated with Candida infection and to analyze other published reports to define clinical characteristics, prognostic data, diagnostic and therapeutic strategies. Study design A computerized search was performed without language restriction using PubMed and Scopus databases. An article was considered eligible for inclusion if it reported cases with Candida thrombophlebitis. Our case was also included in the analysis. Results A total of 16 articles reporting 27 cases of Candida thrombophlebitis were included in our review. The median age of patients was 4 years. In 10 cases there was a thrombophlebitis of peripheral veins; in the re…

0301 basic medicineAntifungal Agentsmedicine.medical_treatmentReviewThrombophlebitislaw.invention0302 clinical medicineRisk FactorslawAmphotericin BThrombosis.030212 general & internal medicineChildPersistent feverAntifungal therapyChildrenCandidaHospital-acquired infectionsCross InfectionAnticoagulantCandidiasislcsh:RJ1-570PrognosisIntensive care unitThrombosisChild PreschoolCentral venous cathetermedicine.drugmedicine.medical_specialtySepsimedicine.drug_class030106 microbiologySepsis03 medical and health sciencesAmphotericin BSepsisInternal medicinemedicineHumansEnoxaparinbusiness.industryAnticoagulantsThrombosislcsh:PediatricsThrombophlebitisNewbornmedicine.diseaseHospital-acquired infectionParenteral nutritionPhlebitisbusinessItalian Journal of Pediatrics
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Uncertainty about the evidence on untargeted antifungal treatment

2016

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0301 basic medicineAntifungalAntifungal AgentsTraditional medicinebusiness.industrymedicine.drug_classAntifungal therapy; Candidaemia; Invasive fungal infections030106 microbiologyUncertaintysepsis fungal infection03 medical and health sciences0302 clinical medicineCandidaemiaInvasive fungal infectionInvasive fungal infectionsInternal MedicineHumansMedicineAntifungal Agent030212 general & internal medicineMED/41 - ANESTESIOLOGIAbusinessAntifungal therapyHuman
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Procalcitonin as a marker of Candida species detection by blood culture and polymerase chain reaction in septic patients

2014

Background: The aim of our study is to test procalcitonin (PCT) as surrogate marker of identification of Candida spp. by blood culture (BC) and real-time-polymerase chain reaction (PCR), whether alone or in association with bacteria, in septic patients.Methods: We performed a single-centre retrospective study. We reviewed the clinical charts of patients with a diagnosis of severe sepsis or septic shock treated at our general intensive care unit from March 2009 to March 2013. We analysed all diagnostic episodes consisting of BC, real-time PCR assay and dosage of PCT. We registered age, sex, white blood count, sequential organ failure assessment score and type of admission between medical or …

Fungal infectionMalePathologyProtein PrecursorSettore MED/41 - AnestesiologiaProcalcitoninlaw.inventionRetrospective StudielawBlood cultureAntifungal therapyPolymerase chain reactionCandidaAged 80 and overmedicine.diagnostic_testbiologyMiddle AgedShock SepticPolymerase chain reactionBlood stream infectionReal-time polymerase chain reactionFemaleProcalcitoninProcalcitonin Sepsis Candida species Blood stream infection Fungal infection Polymerase chain reaction Antifungal therapyhormones hormone substitutes and hormone antagonistsResearch ArticleHumanCalcitoninmedicine.medical_specialtySepsiCalcitonin Gene-Related PeptideReal-Time Polymerase Chain ReactionMicrobiologySepsisSepsisparasitic diseasesCandida speciesmedicineHumansProtein PrecursorsMED/41 - ANESTESIOLOGIAAntifungal therapy; Blood stream infection; Candida species; Fungal infection; Polymerase chain reaction; Procalcitonin; SepsisRetrospective StudiesAgedbusiness.industrySurrogate endpointBiomarkerbacterial infections and mycosesmedicine.diseasebiology.organism_classificationAnesthesiology and Pain MedicineCalcitoninCandida speciebusinessBiomarkersBacteriaBMC Anesthesiology
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Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials…

2019

Pardo-Oviedo, Juan Mauricio/0000-0003-0084-3449; Lopez-Delgado, Juan Carlos/0000-0003-3324-1129; Corradi, Francesco/0000-0002-5588-2608; De Backer, Daniel/0000-0001-9841-5762; POTA, VINCENZO/0000-0001-9999-3388; Tomescu, Dana/0000-0001-9673-5754; Sabetian, Golnar/0000-0001-8764-2150; Girardis, Massimo/0000-0002-2453-0829; Brazzi, Luca/0000-0001-7059-0622; Leone, Marc/0000-0002-3097-758X; Zabolotskikh, Igor Borisovich/0000-0002-3623-2546; De Lange, Dylan/0000-0002-0191-7270; ALMEKHLAFI, GHALEB A./0000-0002-0323-7025; Elke, Gunnar/0000-0002-4948-1605; Grigoras, Ioana/0000-0001-9412-9574; Czuczwar, Miroslaw/0000-0002-9025-6717; Nora, David/0000-0002-1133-7368; Masjedi, Mansoor/0000-0001-6175-9…

Infection riskMaleBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences.Antibiotic resistanceTracte gastrointestinal - MalaltiesDefinitionsCritical Care and Intensive Care MedicineTHERAPYDEFINITIONS:Infections::Intraabdominal Infections [DISEASES]0302 clinical medicineIntensive care; Intra-abdominal infection; Mortality; Multidrug resistance; Peritonitis; Sepsis;[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesObservational studySeptic shockIntensive care; Intra-abdominal infection; Mortality; Multidrug resistance; Peritonitis; SepsisComputingMilieux_MISCELLANEOUSCritical Illness/epidemiology[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseasesBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti.Intraabdominal Infections/epidemiologyAbdominal infectionMulticenter study3. Good healthManagementClinical trialCohort[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyCohort analysisCommunity acquired infectionCohort studyHumanmedicine.medical_specialtyCarbapenem resistanceCritical IllnessPeritoneal dialysisPeritonitisVancomycin resistant enterococcusMajor clinical studyPeritonitisArticle03 medical and health sciencesAntibiotic resistance[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemIntensive careSepsisSettore MED/41 - ANESTESIOLOGIAHumansCritical care medicineHospital infectionAgedScience & TechnologyLiver failureAntibiotic therapymedicine.disease[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyEpidemiologic Studies030228 respiratory systemIntensive Care Unit; Sepsis (Diptera); Septic ShockRisk factorHuman medicineGeneral & internal medicineCongestive heart failureOriginalMultidrug resistanceCohort StudiesRisk FactorsCause of DeathEpidemiologyPrevalenceMedicine and Health SciencesAbdominal abscessSepsis/epidemiologyMiddle agedAntifungal therapy2. Zero hungerPeritonitiAntibiotic agentBiliary tract infectionIntensive care ; Intra-abdominal infection ; Mortality ; Multidrug resistance ; Peritonitis ; SepsisMiddle Aged:infecciones bacterianas y micosis::infección::infecciones intraabdominales [ENFERMEDADES]PREVALENCE:Infections::Sepsis [DISEASES]:técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::estudios de cohortes [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]Methicillin resistant staphylococcus aureusRaonament basat en casosFemaleCritically ill patientLife Sciences & BiomedicineAntifungal agentAdult:Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Predictive value:infecciones bacterianas y micosis::infección::sepsis [ENFERMEDADES]NOSepsisIntra-abdominal infectionCritical Care MedicineInternal medicineGeneral & Internal MedicinemedicineMANAGEMENTJournal Article[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologySepticèmiaMortalitybusiness.industrySeptic shockPancreas diseaseMalnutrition030208 emergency & critical care medicineTyphlitisToxic megacolonIntensive careIntraabdominal InfectionsTherapyLate onset disorderbusiness
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A prospective, randomized study of empirical antifungal therapy for the treatment of chemotherapy-induced febrile neutropenia in children

2012

Given that the rationale for empirical antifungal therapy in neutropenic children is limited and based on adult patient data, we performed a prospective, randomized, controlled trial that evaluated 110 neutropenic children with persistent fever. Those at high risk for invasive fungal infections (IFI) received caspofungin (Arm C) or liposomal amphotericinB (Arm B); those with a lower risk were randomized to receive Arm B, C, or no antifungal treatment (Arm A). Complete response to empirical antifungal therapy was achieved in 90/104 patients (86·5%): 48/56 at high risk (85·7%) [88·0% in Arm B; 83·9% in Arm C (P = 0·72)], and 42/48 at low risk (87·5%) [87·5% in control Arm A, 80·0% Arm B, 94·1…

Malemedicine.medical_specialtyAntifungal AgentsNeutropeniaAntineoplastic AgentsOpportunistic InfectionsLower riskFever of Unknown Originlaw.inventionEchinocandinsLipopeptideschemistry.chemical_compoundRandomized controlled trialCaspofunginlawAmphotericin BInternal medicinemedicineHumansProspective StudiesChildProspective cohort studyempirical antifungal therapy children cancerbusiness.industryPatient SelectionInfantCancerHematologyLength of Staymedicine.diseaseConfidence intervalSurgeryHospitalizationTreatment OutcomeMycoseschemistryChild PreschoolFemaleCaspofunginbusinessEmpiric therapyFebrile neutropeniaBritish Journal of Haematology
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